Alfred Marchal PHD
Alfred Marchal PHD
A Brilliant Scientist and Inventor
He is author of many scientific papers and patents in particular on vitamin C, vitamin K and hyaluronic acid.
He is now board member in pharmaceutical companies and speaker at aesthetic congresses such as IMCAS Paris, AMWC Monaco, Face Cannes and expert in aesthetic medical universities.
He now joins Alphascience as a Chief Research Officer to offer breakthrough new anti-aging and aesthetic treatments to our worldwide clients.
BREAKTHROUGH SCIENTIFIC DISCOVERIES
An infaillible recipe: the observation of nature, knowledge of chemistry molecules and their interactions, scientific analysis of potential interactions between elements, the possible secondary effects, the way an active agent changes according to the elements contained in the skin… All of these, combined with a touch of genius.This is now Alfred Marchal designs his products.
By observing nature, he is able to meet the fundamental requirements of anti-ageing cosmetics and imagine the treatments of the future.
2000: STABILIZATION OF PURE VITAMIN C (L-ASCORBIC ACID) WITH ANTIOXIDANTS
“How do fruits which contain a lot of water manage to keep their vitamin C content stable and active?”
It was this very simple statement that led Alfred Marchal to develop the first serum with a high concentration of stable and active vitamin C, with became a worldwide success.
To achieve this, Alfred Marchal focused on the chemical properties of vitamin C and in particular on its interactions with the substances naturally present in fruits. By understanding how the associative complexes between these different elements are formed, Alfred Marchal had discovered how to stabilize vitamin C in its free and active form also known as L-ascorbic acid.
2003: SPECIFIC DELIVERY SYSTEM FOR VITAMIN K TO TREAT BRUISES AND REDNESS
Alfred Marchal studied the amazing properties of vitamin K on blood vessels and developed the first efficient treatments to treat bruises and redness, especially after aesthetic procedures.
US patent US20030170187A1: “Skin treatments containing nano-sized vitamin K”, Sep. 11, 2003
2005: DISCOVERY OF VITAMIN K1 OXIDE
To improve vitamin K stability, Alfred Marchal discovered a new metabolite: the vitamin K1 oxide with higher activity to further enhance the results of post aesthetic treatments.
Worldwide patent WO2004064798A1: Use of a composition comprising vitamin k1 oxide or a derivative thereof for the treatment and/or the prevention of mammal dermatological lesions.
2006: HYALURONIC ACID IN THE TREATMENT OF WOUND HEALING, SKIN WRINKLES AND LIPS FILLER
European patent EP1884231A1: Cosmetic or pharmaceutical composition containing hyaluronic acid
2006: SYNTHESIS AND STABILIZATION OF SULFORAPHANE
Issued from broccoli, sulforaphane is one of the most effective antioxidant active ingredients.
Alfred Marchal worked on how to synthesize this ingredient and managed to stabilize it for applications in oncologic and anti-aging treatments.
Worldwide patent WO2012010644A1: Procédé de synthèse d’isothiocyanates et leurs derivés et utilisations de ceux-ci
US patent US9254331B2: Sulforaphane stabilization
2011: INNOVATIVE COMPOSITION OF HYALURONIC ACID FOR SKIN AGING AND DERMATOLOGICAL APPLICATIONS
Patent BE1020210A3: Composition dermatologique à base de fragments d’hyaluronate ou d’acide hyaluronique
2013: INTEGRATION AND STABILIZATION OF ASCORBIC ACID (VITAMIN C) IN HYALURONIC FILLER
Patent BE1020210A3: Stable hyaluronic acid gel and a free form of vitamin C and / or a salt thereof
2018: EXCLUSIVE SCIENTIFIC DISCOVERIES WITH ALPHASCIENCE
Since beginning 2018, Alfred Marchal joined Alphascience as CRO (Chief Research Officer) and took over all Alphascience pending research and development projects.
He is also focused in developing state-of-the-art innovations in the following fields:
New anti-aging ingredients
New delivery systems for active molecules
Stabilization of powerful innovative antioxidants and molecules
Highly efficient professional products.
Most of these projects are being patent protected at international level.
With Alfred Marchal, ALPHASCIENCE will offer breakthrough new anti-aging and aesthetic treatments to its worldwide clients.
OTHER PUBLICATIONS
2014 PRIME: International Journal of Aesthetic and Anti-Ageing Medicine – Alfred Marchal interview
2018 LA PELLE : “Un nuovo antiossidante dal cuore della sequoia”|”A new antioxidant from the heart of the sequoia”
2019 Prime Magazine: “Management of the oxidative stress after a procedure aesthetic” | “Management du stress oxydatif après une procedure esthétique”